InBody Application

InBody ApplicationInBody Usages for medical areas

Nutrition care | Baseline for all kinds of diseases

Target Group : Cancer, Wasting disease, Geriatric patients(senior group)
InBody Parameters : FFM(Fat Free Mass) and BCM(Body Cell Mass)
Application : General nutritional assessment for medical Intervention

*BCM(Body Cell Mass) is the sum of proteins and ICW(Intracellular Water)

Fat Free Mass (FFM) Representing Patient’s Overall Status

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COPD* patents tends to lose their body weight rapidly, and it is important to manage their nutrition status

  • Semi-starvation group : high BMI and high FFM
  • Cachexia group : low BMI and low FFM
  • Atrophy group : high BMI and low FFM

Patients who have kept their FFM relatively high (Semi-starvation group) had a good survival rate compared to the other groups

 

*COPD: Chronic obstructive pulmonary disease

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Higher Fat Free Mass among geriatric patients were considered predictors of lower mortality

Also, low BMI as a means of obtaining a survival advantage in the elderly is not supported

Low FFM is a better predictor of mortality then BMI

Surgery | Makes the Best Outcome Together with Nutritional Support

Target Group : Surgical patients
InBody Parameter : FFM, BCM, ECW Ratio
Application : Prediction of surgical output, Preparation for pre-operation period

Surgical Outcome Depends on Patient’s Nutritional Status

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After the liver transplantation, 29% of patients with low BCM were led to in-hospital death from infection when there were only 5% of patients with normal or high BCM

Preoperative BCM has a significant correlation with survival rate to liver-transplanted patients

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Overall changes in the body composition of patients undergoing laparoscopy-assisted (LAG), distal (DG), and total gastrectomy (TG), from before surgery until 6 months after surgery.

The more surgery is aggressive, the more body composition lose was shown

T2DM | Periodical Nutritional Support and Management

Target Group : Type 2 Diabetes
InBody Parameter : FFM, ECW Ratio
Application : Regular nutritional support for T2DM patients

Importance of Leg Muscle Mass

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  • Skeletal Muscle Mass (SMM) tend to DECREASE with DM patients.
  • Leg muscle % is LOW in DM patients than arm muscle %.
  • Leg muscle % DECREASE with higher CVD risk.

Low FFM Increases Insulin Resistance

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HOMA-IR, HbA1C, PDM prevalence, and DM prevalence show significant decrease as skeletal muscle index (SMI) increase.

Hepatology | Nutritional and Edema Assessment

Target group :Liver diseased patients
InBody parameter :BCM, ECW Ratio
Application : Nutritional assessment and edema assessment

BCM to Assess Liver Cirrhotic Patient’s Nutritional Status

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Significantly low BCM with liver cirrhosis is detected from liver cirrhotic patients

Significant negative correlation between BCM and the MELD score in cirrhotic patients aged 40-60 years

BCM is a tool to assess liver cirrhotic patient’s nutritional status

 

MELD score is a parameter which can assess severity of liver damage

ECW Ratio to Predict Development of Ascites

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Segmental ECW ratio was measured and cirrhotic patients with grade 1 or 2 ascites had significantly higher ECW ratios of the trunk than those with no ascites.

ECW ratio is reliable tool for the prediction of the risk of developing ascites.

Nephrology | Accurate Water Management is a Key

Target group : Hemo-dialysis, Peritoneal dialysis patients
InBody parameter : ECW Ratio, Segmental ECW Ratio
Application : Dry weight assessment, Diagnose of circulatory disease

ECW Ratio of the InBody is Efficient to Assess Dry Weight (DW)

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DW is determined by subtracting the water volume when the patient’s ECW ratio fall under 0.380 from the current weight.

This study have investigated whether the InBody was useful when assessing DW of dialysis patients by monitoring body water and the ECW ratio.

Assessment of DW using normal ECW ratio showing a significant correlation with clinical DW

Different ECW Ratio is applied According to Complications

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Normal healthy people usually have 0.380 as a normal value of ECW ratio, however, this study is indicating dialysis patients with other complications should not consider 0.380 as a normal value.

Normal Renal Patients: 0.380

DM Renal Patients: 0.398

HypoAlb Renal Patients: 0.397

DM / HypoAlb: 0.404

Dry weight should be considered higher when the patients are having complications

Detect Circulatory Problem with Segmental ECW Ratio

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Deep vein thrombosis (DVT) is caused by blood clots in the veins of lower limb. Usually occur in patients who have been bed-ridden for a long time, patients with trauma, and patients with malignant tumor as the blood in the deep veins easily form thrombosis. 

 

DVT can be found out with segmental ECW Ratio
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Cardiology | Cardiac Burden can be Managed when Managing Water

Target group : Cardiac failure patients
InBody parameter : ECW Ratio
Application : Cardiac failure management

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Management of ECW Ratio may reduce reoccurrence of cardiac failure

Control: Patient group without regular treatment

CM: Patient group cared by a heart failure team

EI: Cared by same team as in CM and also cared by using edema index

EI group had better survival rate compared to other groups

Drug Prescription | For better decision of drug dosage

Target group : Surgical patients
InBody parameter : FFM
Application : Drug dosage prescription

Total Clearance is Depend on Cardiac Output (CO)

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Total clearance is increased two-fold in the obese vs normal weight subjects. (Obese individuals have increased FFM)

Obese individuals have an increased Cardiac Output (CO)

CO is an important determinant in the early distribution kinetics of i.v. drugs.

 

Fig 2 Relationship between propofol induction dose and body weight in morbidly obese (MO) subjects. There is a significant relationship between induction dose and body weight in MO subjects given propofol based on LBM.

British Journal of Anaesthesia105 (S1): i16–i23 (2010).

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Estimated FFM using height and weight may cause significant adverse effect. Difference between actual FFM and estimated FFM had a correlation with actual plasma drug concentration. High plasma drug concentration may cause adverse respiratory events.

Actual measurement of FFM is important for better decision of drug dosage.