InBody Application - InBody Usages for medical areas
Nutrition care | Baseline for all kinds of diseases
Target Group : Cancer, Wasting disease, Geriatric patients(senior group)
InBody Parameters : FFM(Fat Free Mass) and BCM(Body Cell Mass)
Application : General nutritional assessment for medical Intervention
*BCM(Body Cell Mass) is the sum of proteins and ICW(Intracellular Water)
Fat Free Mass (FFM) Representing Patient’s Overall Status
COPD* patents tends to lose their body weight rapidly, and it is important to manage their nutrition status
- Semi-starvation group : high BMI and high FFM
- Cachexia group : low BMI and low FFM
- Atrophy group : high BMI and low FFM
Patients who have kept their FFM relatively high (Semi-starvation group) had a good survival rate compared to the other groups
*COPD: Chronic obstructive pulmonary disease
Higher Fat Free Mass among geriatric patients were considered predictors of lower mortality
Also, low BMI as a means of obtaining a survival advantage in the elderly is not supported
Low FFM is a better predictor of mortality then BMI
Surgery | Makes the Best Outcome Together with Nutritional Support
Target Group : Surgical patients
InBody Parameter : FFM, BCM, ECW Ratio
Application : Prediction of surgical output, Preparation for pre-operation period
Surgical Outcome Depends on Patient’s Nutritional Status
After the liver transplantation, 29% of patients with low BCM were led to in-hospital death from infection when there were only 5% of patients with normal or high BCM
Preoperative BCM has a significant correlation with survival rate to liver-transplanted patients
Overall changes in the body composition of patients undergoing laparoscopy-assisted (LAG), distal (DG), and total gastrectomy (TG), from before surgery until 6 months after surgery.
The more surgery is aggressive, the more body composition lose was shown
T2DM | Periodical Nutritional Support and Management
Target Group : Type 2 Diabetes
InBody Parameter : FFM, ECW Ratio
Application : Regular nutritional support for T2DM patients
Importance of Leg Muscle Mass
- Skeletal Muscle Mass (SMM) tend to DECREASE with DM patients.
- Leg muscle % is LOW in DM patients than arm muscle %.
- Leg muscle % DECREASE with higher CVD risk.
Low FFM Increases Insulin Resistance
HOMA-IR, HbA1C, PDM prevalence, and DM prevalence show significant decrease as skeletal muscle index (SMI) increase.
Hepatology | Nutritional and Edema Assessment
Target group :Liver diseased patients
InBody parameter :BCM, ECW Ratio
Application : Nutritional assessment and edema assessment
BCM to Assess Liver Cirrhotic Patient’s Nutritional Status
Significantly low BCM with liver cirrhosis is detected from liver cirrhotic patients
Significant negative correlation between BCM and the MELD score in cirrhotic patients aged 40-60 years
BCM is a tool to assess liver cirrhotic patient’s nutritional status
MELD score is a parameter which can assess severity of liver damage
ECW Ratio to Predict Development of Ascites
Segmental ECW ratio was measured and cirrhotic patients with grade 1 or 2 ascites had significantly higher ECW ratios of the trunk than those with no ascites.
ECW ratio is reliable tool for the prediction of the risk of developing ascites.
Nephrology | Accurate Water Management is a Key
Target group : Hemo-dialysis, Peritoneal dialysis patients
InBody parameter : ECW Ratio, Segmental ECW Ratio
Application : Dry weight assessment, Diagnose of circulatory disease
ECW Ratio of the InBody is Efficient to Assess Dry Weight (DW)
DW is determined by subtracting the water volume when the patient’s ECW ratio fall under 0.380 from the current weight.
This study have investigated whether the InBody was useful when assessing DW of dialysis patients by monitoring body water and the ECW ratio.
Assessment of DW using normal ECW ratio showing a significant correlation with clinical DW
Different ECW Ratio is applied According to Complications
Normal healthy people usually have 0.380 as a normal value of ECW ratio, however, this study is indicating dialysis patients with other complications should not consider 0.380 as a normal value.
Normal Renal Patients: 0.380
DM Renal Patients: 0.398
HypoAlb Renal Patients: 0.397
DM / HypoAlb: 0.404
Dry weight should be considered higher when the patients are having complications
Detect Circulatory Problem with Segmental ECW Ratio
Deep vein thrombosis (DVT) is caused by blood clots in the veins of lower limb. Usually occur in patients who have been bed-ridden for a long time, patients with trauma, and patients with malignant tumor as the blood in the deep veins easily form thrombosis.
DVT can be found out with segmental ECW Ratio
Cardiology | Cardiac Burden can be Managed when Managing Water
Target group : Cardiac failure patients
InBody parameter : ECW Ratio
Application : Cardiac failure management
Management of ECW Ratio may reduce reoccurrence of cardiac failure
Control: Patient group without regular treatment
CM: Patient group cared by a heart failure team
EI: Cared by same team as in CM and also cared by using edema index
EI group had better survival rate compared to other groups
Drug Prescription | For better decision of drug dosage
Target group : Surgical patients
InBody parameter : FFM
Application : Drug dosage prescription
Total Clearance is Depend on Cardiac Output (CO)
Total clearance is increased two-fold in the obese vs normal weight subjects. (Obese individuals have increased FFM)
Obese individuals have an increased Cardiac Output (CO)
CO is an important determinant in the early distribution kinetics of i.v. drugs.
Fig 2 Relationship between propofol induction dose and body weight in morbidly obese (MO) subjects. There is a significant relationship between induction dose and body weight in MO subjects given propofol based on LBM.
British Journal of Anaesthesia105 (S1): i16–i23 (2010).
Estimated FFM using height and weight may cause significant adverse effect. Difference between actual FFM and estimated FFM had a correlation with actual plasma drug concentration. High plasma drug concentration may cause adverse respiratory events.
Actual measurement of FFM is important for better decision of drug dosage.